Several other medicines may perhaps change the blood amounts of promethazine/phenylephrine/codeine, and vice versa. Tell your healthcare company about all medicines that you simply consider or have not long ago taken.
The dose of the drugs are going to be diverse for different clients. Follow your doctor's orders or perhaps the Instructions to the label. The following information and facts features only the common doses of the medication. If your dose is different, usually do not improve it Unless of course your doctor tells you to do so.
Extensive-expression usage of promethazine/phenylephrine/codeine could affect your power to grow to be Expecting or have a husband or wife pregnant. Speak with your Health care service provider In case you have any considerations.
Glaucoma. Glaucoma is actually a condition which will cause hassle looking at or blindness due to harm to the optic nerve within your eye. Promethazine/phenylephrine/codeine may well boost pressure inside the eye and worsen slim-angle glaucoma.
Test together with your healthcare doctor or dentist just before getting any of the above mentioned When you or your son or daughter are using this medication.
Even though the exact system of motion of codeine remains mysterious, it is mostly considered mediated throughout the agonism of opioid receptors, notably the mu-opioid receptors.4 Morphine was Formerly postulated to add to your analgesic outcome of codeine mainly because of the O-demethylation of codeine to morphine by CYP2D6. Particularly, CYP2D6 weak metabolizer did not encounter the analgesic impact of codeine.two,ten However, This is often unlikely to become the key system of motion of codeine as only 5% of codeine is metabolized to morphine.
You may additionally experience lightheaded when having up abruptly from a lying or sitting place, so arise gradually.
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Using this medicine with any of the next may well lead to a heightened risk of sure side effects but can be unavoidable occasionally. If used jointly, your medical professional might change the check here dose or how often you utilize this drugs, or Supply you with Distinctive Directions about using food stuff, alcohol, or tobacco.
Elevated prescribing of opioids and antidepressants means more sufferers are taking medicine from Every class. But some combinations Have a very significant hazard of toxicity.
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In choosing to use a medication, the risks of getting the drugs has to be weighed against The great it is going to do. This really is a choice both you and your physician is likely to make. For this drugs, the following really should be regarded:
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